4 Results for "

Pep2m

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Pep2m" in MCE Product Catalog:

Cat. No.: HY-P1399
CAS No.: 1423381-07-0
Synonyms: Myr-Pep2m
Target:  

PKC

Research Areas:  

Neurological Disease

Pep2m, myristoylated (Myr-Pep2m) is a cell-permeable peptide. Pep2m, myristoylated can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions. PKMζ is an autonomously active isozyme of protein kinase C (PKC) [2].
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Cat. No.: HY-P1399A
Synonyms: Myr-Pep2m TFA
Target:  

PKC

Research Areas:  

Neurological Disease

Pep2m, myristoylated TFA (Myr-Pep2m TFA) is a cell-permeable peptide. Pep2m, myristoylated TFA can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions. PKMζ is an autonomously active isozyme of protein kinase C (PKC) [2].
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Cat. No.: HY-P1058
CAS No.: 243843-42-7
Target:  

iGluR

Research Areas:  

Neurological Disease

Pep2m is a peptide receptor inhibitor. Pep2m inhibits the interaction between the C-terminus of the AMPA-type glutamate receptor (GluA2) subunit and N-ethylmaleimide-sensitive fusion protein (NSF). Pep2m prevents synaptic long-term depression (LTD). Pep2m can reduce postsynaptic currents in neurons, AMPA-mediated currents in cultured hippocampal neurons, and AMPA receptor surface expression [1] [2] [3] [4] [5].
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Cat. No.: HY-P1057
CAS No.: 243843-43-8
Target:  

iGluR

Research Areas:  

Neurological Disease

Pep4c is an inactive control peptide for Pep2m (HY-P1058). Pep4c lacks functional activity to disrupt Protein Interacting with C Kinase 1 (PICK1)-AMPA receptor (GluA2) or N-ethylmaleimide-sensitive factor (NSF)-GluA2 interactions. Pep4c is used as a negative control in experiments to validate the specificity of Pep2m's effects on AMPA receptor trafficking and synaptic plasticity [1] [2] [3] [4] [5] [6].
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