1 Result for "

Phe231

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Phe231" in MCE Product Catalog:

Cat. No.: HY-187206
Target:  

Cytochrome P450

Research Areas:  

Cancer

CYP1B1-IN-15 is a CYP1B1 inhibitor with an IC50 of 1.47 nM, and it exhibits high selectivity against six major CYP subtypes. CYP1B1-IN-15 exerts competitive inhibitory effects by competing with substrates for binding to the active site of CYP1B1. CYP1B1-IN-15 enhances the inhibitory effect of Paclitaxel (HY-B0015) on the proliferation of paclitaxel-resistant cancer cells, and inhibits the migration and invasion of paclitaxel-resistant cancer cells. CYP1B1-IN-15 can be used in studies related to paclitaxel-resistant non-small cell lung cancer .
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