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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
Phototherapy
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "Phototherapy" in MCE Product Catalog:
Cat. No.: HY-162045
Target:
Research Areas:
Ru-4T is a phototherapy agent. Ru-4T has phototherapeutic efficacy (PI = 114,000) against melanoma cells (SK-MEL-28) under broad-band visible light (400-700 nm) with EC50 values of 740 pM .
Cat. No.: HY-162958
CAS No.: 3052251-17-6
Photosensitizer-6 (Compound 4) is a gold (I) complex and exhibits inhibitory activity against TrxR. Photosensitizer-6 induces apoptosis in 4T1 cell, targets and eradicates tumors through chemo-phototherapy and immunogenic cell death under light exposure. Photosensitizer-6 can be used for tumor imaging .
Cat. No.: HY-176859
[Ru(dpp)(bpy)(mtmp)](PF6)2 (Compound 5) is a trisheteroleptic ruthenium complex. [Ru(dpp)(bpy)(mtmp)](PF6)2 has a light-activated anticancer activity. [Ru(dpp)(bpy)(mtmp)](PF6)2 can selectively cleave off upon green light irradiation, thereby releasing a phototoxic ruthenium-based photoproduct that binds to nuclear DNA, induces DNA damage and apoptosis in cancer cells. [Ru(dpp)(bpy)(mtmp)](PF6)2 can be used for phototherapy of cancers like conjunctival melanoma research .
Cat. No.: HY-184452
Research Areas:
BNNC is a Photomolecular glue . BNNC selectively releases (R)-CR8 (HY-18340) (a Cyclin K molecular glue) and BSS-Et in hypoxic tumor microenvironments, thereby triggering Cyclin K degradation dependent on the ubiquitin-proteasome pathway. BNNC generates ROS and singlet oxygen in hypoxic tumor cells under light irradiation. BNNC enhances DNA damage and Apoptosis through the combined effects of Cyclin K degradation and phototherapy. BNNC enhances the tumor selectivity of molecular glue via specific activation in hypoxic tumor microenvironments. BNNC can be used in breast cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
