2 Results for "

Pibrozelesin

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Pibrozelesin" in MCE Product Catalog:

Cat. No.: HY-19137
CAS No.: 154889-68-6
Synonyms: KW 2189 free base
Target:  

Antibiotic

Research Areas:  

Infection Cancer

Pibrozelesin (KW 2189 free base) is the derivative of antibiotic Duocarmycin B2. Pibrozelesin exhibits antitumor activity, inhibits proliferation of cell H69 with an IC50 of 1.9 μM. Pibrozelesin induces the DNA strand breaks upon activation via carboxyl esterase .
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Cat. No.: HY-105223A
CAS No.: 148778-32-9
Target:  

Drug Intermediate

Research Areas:  

Cancer

Pibrozelesin hydrobromide is a hydrolytic prodrug of Carzelesin (HY-19601). Pibrozelesin hydrobromide has an anticancer activity. Carzelesin is a cyclopropylpyrroloindole precursor molecule and effectively inhibits tumor growth. Carzelesin may be used in cancer research .
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