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Cat. No.: HY-105223A

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Pibrozelesin hydrobromide

Pibrozelesin hydrobromide is a hydrolytic prodrug of Carzelesin (HY-19601). Pibrozelesin hydrobromide has an anticancer activity. Carzelesin is a cyclopropylpyrroloindole precursor molecule and effectively inhibits tumor growth. Carzelesin may be used in cancer research.

For research use only. We do not sell to patients.

CAS No.: 148778-32-9
Formula: C₃₂H₃₇Br₂N₅O₈
Molecular Weight:779.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

Pibrozelesin hydrobromide Chemical Structure

CAS No.: 148778-32-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 148778-32-9
Molecular Weight 779.47
Formula C₃₂H₃₇Br₂N₅O₈
SMILES

O=C(C(C1=C(C(CN2C(C3=CC4=C(N3)C(OC)=C(OC)C(OC)=C4)=O)CBr)C2=C5)=C(C)NC1=C5OC(N6CCN(CC6)C)=O)OC.Br
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Felber JG, et al. 40 Years of Duocarmycins: A Graphical Structure/Function Review of Their Chemical Evolution, from SAR to Prodrugs and ADCs. JACS Au. 2022 Nov 15;2(12):2636-2644. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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