10 Results for "

RAMP1

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "RAMP1" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P1548
CAS No.: 101462-82-2
Synonyms: Human β-CGRP; CGRP-II (Human)
β-CGRP, human (Human β-CGRP) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells [1].
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1
1 Cited Publications
Cat. No.: HY-P1548A
Synonyms: Human β-CGRP TFA; CGRP-II (Human) TFA
β-CGRP, human TFA (Human β-CGRP TFA) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells [1].
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1
1 Cited Publications
Cat. No.: HY-P82073
Synonyms: CRLR activity-modifying protein 1; Calcitonin-receptor-like receptor activity-modifying protein 1

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-RS11638
Research Areas:  

Others

RAMP1 Human Pre-designed siRNA Set A contains three designed siRNAs for RAMP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS19031
Research Areas:  

Others

Ramp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ramp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS25520
Research Areas:  

Others

Ramp1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ramp1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P4863
CAS No.: 1678415-18-3
Target:  

CGRP Receptor

Biotinyl-Amylin (human) is a biotin-labeled derivative of Amylin, amide, human (HY-P1070). Biotinyl-Amylin (human) acts as a competitive agonist for the Calcitonin Receptor (CTR) and for the Amylin receptors (AMY1, AMY2, and AMY3) formed by the association of CTR with RAMP1/2/3. By mimicking endogenous human amylin, Biotinyl-Amylin (human) binds to and activates CTR and AMY receptors, thereby initiating downstream signaling pathways involving cAMP, CREB, and ERK1/2, while retaining high-affinity receptor binding and activation capabilities. Biotinyl-Amylin (human) is primarily utilized in studies investigating the metabolic regulatory mechanisms underlying obesity and diabetes; it is also applicable to pharmacological research, receptor localization studies, and ligand-binding assays related to Amylin receptors in the context of Alzheimer's disease [1].
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Cat. No.: HY-P1548B
Synonyms: Human β-CGRP acetate; CGRP-II (Human) acetate
β-CGRP, human acetate (Human β-CGRP acetate) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells [1].
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Cat. No.: HY-P82073A
Synonyms: CRLR activity-modifying protein 1; Calcitonin-receptor-like receptor activity-modifying protein 1

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-183142
CAS No.: 2252341-45-8
Target:  

CGRP Receptor

Research Areas:  

Cancer

CLR/RAMP3-receptor antagonist-1 is a selective antagonist of the CLR/RAMP3 receptor (CLR/RAMP3, AM2 receptor), with pIC50 values of 5.86, 9.21 and 9.07 against AM1 (CLR/RAMP2), AM2 (CLR/RAMP3) and CGRP (CLR/RAMP1) receptors, respectively. CLR/RAMP3-receptor antagonist-1 reduces the levels of pancreatic cancer progression markers, induces apoptosis in vitro, and prolongs survival in mouse models of pancreatic cancer. CLR/RAMP3-receptor antagonist-1 can be used in pancreatic cancer-related research [1].
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