1 Result for "

RI-OR2-TAT

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RI-OR2-TAT" in MCE Product Catalog:

Cat. No.: HY-P10824
CAS No.: 1430219-69-4
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

RI-OR2-TAT is a brain-penetrant inhibitor of β-Amyloid oligomerization, which is produced by adding the HIV protein transduction domain TAT to RI-OR2. RI-OR2-TAT binds to Aβ42 fibrils with a Kd value of 58-125 nM. RI-OR2-TAT reduces aggregation and plaque levels, reduces activation of microglia and oxidative damage, and increases the number of young neurons in the dentate gyrus .
loading...
    loading...