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Results for "

RcCHAD

" in MedChemExpress (MCE) Product Catalog:

By Targets:	P2X Receptor (1)
By Research Areas:	Neurological Disease (1)
Oligonucleotides:	Nucleotide Analogs (1) Adenine Nucleotide (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Diadenosine pentaphosphate pentasodium	P2X Receptor	Neurological Disease
Diadenosine pentaphosphate pentasodium is an agonist and negative modulator of the P2X1 receptor, an endogenous vasoactive purine dinucleotide that can be isolated from platelets. Diadenosine pentaphosphate pentasodium mediates negative regulation of dendrite growth and number by activating homologous and heterologous P2X1 receptors, which triggers a transient and moderate increase in intracellular calcium levels within dendritic growth cones. Diadenosine pentaphosphate pentasodium is widely present in secretory vesicles such as platelets, chromaffin cells and brain synaptosomes, and exhibits selective activity on dendrite growth of cultured hippocampal neurons, inhibiting only dendrite growth without affecting axon growth. Diadenosine pentaphosphate pentasodium has a weaker ability to compete with *RcCHAD* for binding to polyP than short-chain polyPs .

Cat. No.	Product Name		Classification

Diadenosine pentaphosphate pentasodium		Nucleotide Analogs Adenine Nucleotide
Diadenosine pentaphosphate pentasodium is an agonist and negative modulator of the P2X1 receptor, an endogenous vasoactive purine dinucleotide that can be isolated from platelets. Diadenosine pentaphosphate pentasodium mediates negative regulation of dendrite growth and number by activating homologous and heterologous P2X1 receptors, which triggers a transient and moderate increase in intracellular calcium levels within dendritic growth cones. Diadenosine pentaphosphate pentasodium is widely present in secretory vesicles such as platelets, chromaffin cells and brain synaptosomes, and exhibits selective activity on dendrite growth of cultured hippocampal neurons, inhibiting only dendrite growth without affecting axon growth. Diadenosine pentaphosphate pentasodium has a weaker ability to compete with *RcCHAD* for binding to polyP than short-chain polyPs .

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