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Results for "

SCC-4

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-172526
    4A3-SCC-10

    		Liposome Cancer
    4A3-SCC-10 is a biodegradable ionizable lipid containing disulfide bonds. 4A3-SCC-10 can be used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. 4A3-SCC-10 can be used for broad applications such as gene editing, vaccine, and cancer detection .
    4A3-SCC-10
  • HY-P99719
    Lupartumab Amadotin

    BAY 1129980; Anti-C4.4a antibody-drug conjugates

    		 Antibody-Drug Conjugates (ADCs) Cancer
    Lupartumab Amadotin (BAY 1129980) is an antibody–drug conjugate (ADC) consisting of a fully human C4.4A (LYPD3)-targeting mAb (BAY 1135626) (HY-147281) conjugated to a novel, highly potent derivative of the microtubule-disrupting cytotoxic drug auristatin via a noncleavable alkyl hydrazide linker. Lupartumab Amadotin can be used for the research of non-small cell lung cancer .
    Lupartumab Amadotin
  • HY-10071A
    Y-27632 hydrochloride hydrate
    395+ Cited Publications

    		 ROCK NF-κB Apoptosis Autophagy Akt mTOR NADPH Oxidase Reactive Oxygen Species (ROS) PAK Ras Neurological Disease Inflammation/Immunology Cancer
    Y-27632 hydrochloride hydrate is a ROCK inhibitor with Ki values of 220 nM and 300 nM for ROCK1 and ROCK2, respectively. Y-27632 hydrochloride hydrate exerts anti-inflammatory and immunomodulatory effects in systemic lupus erythematosus models by inhibiting the ROCK/NF-κB pathway. Y-27632 hydrochloride hydrate enhances autophagy by inhibiting the AKT/mTOR pathway, thereby inducing apoptosis apoptosis in oral squamous cell carcinoma. Y-27632 hydrochloride hydrate induces the formation of tunneling nanotubes in ARPE-19 cells and significantly enhances mitochondrial transfer through these channels. Y-27632 hydrochloride hydrate promotes neurite outgrowth in PC12 cells by activating the Rac1/NOX1/ROS/AKT/PAK1 signaling cascade [4] .
    Y-27632 hydrochloride hydrate
  • HY-RS08175
    MAU2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    MAU2 Human Pre-designed siRNA Set A contains three designed siRNAs for MAU2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    MAU2 Human Pre-designed siRNA Set A
    MAU2 Human Pre-designed siRNA Set A

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