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3 Results for "
SD91
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "SD91" in MCE Product Catalog:
Cat. No.: HY-150251
CAS No.: 2497583-03-4
Synonyms: STAT3 degrader-2
SD-91 (STAT3 degrader-2), a product of the hydrolysis of SD-36 (HY-129602), is a selective PROTAC-based STAT3 degrader with a Ki of 5.5 nM. SD-91 displays >300-fold selectivity over other STAT family protein members. SD-91 potently induces degradation of STAT3 protein in cells. SD-91 has anticancer effects, such as myeloid leukemia, lymphoma (Pink: ligand for target protein (HY-150895); Black: linker; Blue: E3 ligase ligand; E3 ligase ligand+linker: HY-176506) .
Cat. No.: HY-176506
Research Areas:
Deoxy-thalidomide-alkyne-hexanoic acid is a E3 ligase ligand-linker conjugate that can be used for synthesis of PROTAC degrader SD-91 (HY-150251) .
Cat. No.: HY-150895
CAS No.: 2754428-37-8
Research Areas:
SI-191 is a STAT3 inhibitor and a target protein ligand. SI-191 inhibits the growth of cancer cells. SI-191 can be used in the research of acute leukemia and lymphoma. SI-191 can be used for the synthesis of PROTAC SD-91 (HY-150251) .
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