Deoxy-thalidomide-alkyne-hexanoic acid
Deoxy-thalidomide-alkyne-hexanoic acid is a E3 ligase ligand-linker conjugate that can be used for synthesis of PROTAC degrader SD-91 (HY-150251).
For research use only. We do not sell to patients.
- Formula: C21H24N2O4
- Molecular Weight:368.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 368.43
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Formula C21H24N2O4
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SMILES
O=C(O)CCCCCC#CC1=C2C(C(N(C3C(NCCC3)=O)C2)=O)=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)