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Results for "

SDHI

" in MedChemExpress (MCE) Product Catalog:

14

Inhibitors & Agonists

2

Biochemical Assay Reagents

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-119976
    Boscalid
    1 Publications Verification

    		 Environmental Pollutants Apoptosis Fungal Mitochondrial Metabolism Succinate Dehydrogenase Infection
    Boscalid is a succinate dehydrogenase (SDHI) inhibitor with antifungal activity. Boscalid binds to the ubiquinone-binding site of fungal mitochondrial complex II, blocks ATP production and aerobic respiration, exhibits good control efficacy against a variety of plant fungal diseases including gray mold, sclerotinia rot and powdery mildew, and is widely used for disease control in agriculture. Boscalid induces apoptosis, altered lipid metabolism, mitochondrial dysfunction, respiratory impairment, oxidative stress, ROS accumulation and neurodevelopmental disorders in zebrafish. Boscalid reduces foraging ability, shortens median death time and causes chronic toxicity in exposed honeybees. Boscalid also possesses genotoxicity, cytotoxicity, elevated mitochondrial superoxide levels and early-stage apoptosis .
    Boscalid
  • HY-W753375
    Fluindapyr

    		Environmental Pollutants Fungal Succinate Dehydrogenase Infection
    Fluindapyr is a broad-spectrum pyrazolamide chiral fungicide of succinate dehydrogenase inhibitor (SDHIs) with broad bactericidal spectrum and good efficacy. Fluopimomide is effective against M. incognita in vitro and application of fuopimomide shows some growth promotion effect in cucumber .
    Fluindapyr
  • HY-139161
    Penflufen

    		Environmental Pollutants Fungal Infection
    Penflufen is a highly efficient, broad-spectrum succinate dehydrogenase inhibitor (SDHI). Penflufen can be used as a fungicide and has broad bioactivity against many fungal diseases, including potato black scurf, wheat sharp eyespot, rice sheath blight, and root rot in peanut and other similar fungal diseases .
    Penflufen
  • HY-139839
    Y12196

    		Fungal Infection
    Y12196 is a novel succinate dehydrogenase inhibitor (SDHI) which exhibits strong fungicidal activity against F. graminearum.
    Y12196
  • HY-176413
    SDH-IN-27

    		Fungal Infection
    SDH-IN-27 (Compound Q18) is a succinate dehydrogenase inhibitor (SDHI) (IC50: 9.7 mg/L). SDH-IN-27 induces mycelial morphology changes and lipid peroxidation, and exhibits antifungal activity against C. camelliae (EC50: 6.0 mg/L). SDH-IN-27 is an ergosterol biosynthesis inhibitor (EBI) that binds to the active site of CYP51, ultimately leading to cell death of pathogenic fungi .
    SDH-IN-27
  • HY-149653
    SDH-IN-10

    		Fungal Infection
    SDH-IN-10 is a potent succinate dehydrogenase inhibitor (SDHI) with antifungal effects .
    SDH-IN-10
  • HY-W753375R
    Fluindapyr (Standard)

    		Reference Standards Fungal Succinate Dehydrogenase Infection
    Clenbuterol (hydrochloride) (Standard) is the analytical standard of Clenbuterol (hydrochloride). This product is intended for research and analytical applications. Clenbuterol (NAB-365) hydrochloride, a selective β2-adrenergic agonist, enhances skeletal muscle strength and hypertrophy. Clenbuterol hydrochloride induces growth factor mRNA, activates astrocytes, and protects rat brain tissue against ischemic damage .
    Fluindapyr (Standard)
  • HY-139161R
    Penflufen (Standard)

    		Fungal Reference Standards Infection
    Penflufen (Standard) is the analytical standard of Penflufen. This product is intended for research and analytical applications. Penflufen is a highly efficient, broad-spectrum succinate dehydrogenase inhibitor (SDHI). Penflufen can be used as a fungicide and has broad bioactivity against many fungal diseases, including potato black scurf, wheat sharp eyespot, rice sheath blight, and root rot in peanut and other similar fungal diseases .
    Penflufen (Standard)
  • HY-158321
    SDH-IN-15

    		Fungal Succinate Dehydrogenase Infection
    SDH-IN-15 (Compound 5e) is an inhibitor of succinate dehydrogenase (SDH) (IC50=2.04 μM). SDH-IN-15 has significant antifungal activity. SDH-IN-15 blocks the mitochondrial respiratory chain of the fungus through inhibition of SDH, resulting in fungal death .
    SDH-IN-15
  • HY-174390
    SDH-IN-29

    		Fungal Succinate Dehydrogenase Infection
    SDH-IN-29 (Compound A33) is a SDH inhibitor with an IC50 of 0.0709 μM. SDH-IN-29 has a broad spectrum of antifungal activities (EC50s of 0.356, 0.798 and 0.146 μg/mL for Fusarium graminearum, Sclerotinia sclerotiorum, and Rhizoctonia solani, respectively). SDH-IN-29 has moderate to significant protective effects against rice blast, wheat scab and cucumber powdery mildew .
    SDH-IN-29
  • HY-119976S
    Boscalid-d4

    		Isotope-Labeled Compounds Apoptosis Fungal Mitochondrial Metabolism Succinate Dehydrogenase Others
    Boscalid-d4 is the deuterium labeled Boscalid. Boscalid is a succinate dehydrogenase (SDHI) inhibitor with antifungal activity. Boscalid binds to the ubiquinone-binding site of fungal mitochondrial complex II, blocks ATP production and aerobic respiration, exhibits good control efficacy against a variety of plant fungal diseases including gray mold, sclerotinia rot and powdery mildew, and is widely used for disease control in agriculture. Boscalid induces apoptosis, altered lipid metabolism, mitochondrial dysfunction, respiratory impairment, oxidative stress, ROS accumulation and neurodevelopmental disorders in zebrafish. Boscalid reduces foraging ability, shortens median death time and causes chronic toxicity in exposed honeybees. Boscalid also possesses genotoxicity, cytotoxicity, elevated mitochondrial superoxide levels and early-stage apoptosis .
    Boscalid-d4
  • HY-119976R
    Boscalid (Standard)

    		Reference Standards Apoptosis Fungal Mitochondrial Metabolism Succinate Dehydrogenase Infection
    Boscalid (Standard) is the analytical standard of Boscalid. This product is intended for research and analytical applications. Boscalid is a succinate dehydrogenase (SDHI) inhibitor with antifungal activity. Boscalid binds to the ubiquinone-binding site of fungal mitochondrial complex II, blocks ATP production and aerobic respiration, exhibits good control efficacy against a variety of plant fungal diseases including gray mold, sclerotinia rot and powdery mildew, and is widely used for disease control in agriculture. Boscalid induces apoptosis, altered lipid metabolism, mitochondrial dysfunction, respiratory impairment, oxidative stress, ROS accumulation and neurodevelopmental disorders in zebrafish. Boscalid reduces foraging ability, shortens median death time and causes chronic toxicity in exposed honeybees. Boscalid also possesses genotoxicity, cytotoxicity, elevated mitochondrial superoxide levels and early-stage apoptosis .
    Boscalid (Standard)
  • HY-179139
    SDH-IN-40

    		Fungal Infection
    SDH-IN-40 (compound A7) is a succinate dehydrogenase inhibitor (SDHI). SDH-IN-40 exhibits strong inhibitory effects on F. graminearum (IC50 = 34.33 μM). SDH-IN-40 can be used for research on fungal infections .
    SDH-IN-40
  • HY-185574
    Enpyracymid

    		Succinate Dehydrogenase Fungal Infection
    Enpyracymid is a succinate dehydrogenase inhibitor (SDHI) fungicide with fungicidal activity against fungal. It can be used in studies related to Fusarium head blight (FHB) .
    Enpyracymid

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