1 Result for "

SH-1573

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "SH-1573" in MCE Product Catalog:

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Cat. No.: HY-164526
CAS No.: 2376068-96-9
Research Areas:  

Cancer

SH1573 is an orally active mIDH2 inhibitor. SH1573 has a strong and selective inhibitory effect on mIDH2 R140Q protein (IC50=4.78 nmol/L), and can effectively reduce the production of the carcinogenic metabolite 2-hydroxyglutarate (2-HG) in animal models, cell lines, serum and tumors. SH1573 can be used for the study of acute myeloid leukemia (AML) .
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