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SIRT6-IN-2

" in MedChemExpress (MCE) Product Catalog:
製品番号 製品名 Target 研究分野 構造式
  • HY-103721
    SIRT6-IN-2

    		Sirtuin Metabolic Disease Inflammation/Immunology Cancer
    SIRT6-IN-2 (Compound 5) is a selective and competitive SIRT6 inhibitor (IC50: 34 μM). SIRT6-IN-2 increases acetylation of H3K9 and increases glucose uptake in cultured cells. SIRT6-IN-2 also reduces T cell proliferation. SIRT6-IN-2 has immunosuppressive and chemosensitizing effects .
    SIRT6-IN-2
  • HY-123194
    SIRT2/6-IN-1

    		Histone Demethylase Sirtuin Metabolic Disease
    SIRT2/6-IN-1 (Compound 5) is a SIRT6/SIRT2 inhibitor, with IC50s of 106 μM and 114 μM. SIRT2/6-IN-1 increases H3K9 acetylation, increases glucose uptake and reduces TNF-α secretion in cells .
    SIRT2/6-IN-1
  • HY-103721R
    SIRT6-IN-2 (Standard)

    		Sirtuin Reference Standards Metabolic Disease Inflammation/Immunology Cancer
    SIRT6-IN-2 (Standard) is the analytical standard of SIRT6-IN-2 (HY-103721). This product is intended for research and analytical applications. SIRT6-IN-2 (Compound 5) is a selective and competitive SIRT6 inhibitor (IC50: 34 μM). SIRT6-IN-2 increases acetylation of H3K9 and increases glucose uptake in cultured cells. SIRT6-IN-2 also reduces T cell proliferation. SIRT6-IN-2 has immunosuppressive and chemosensitizing effects .
    SIRT6-IN-2 (Standard)
  • HY-169159
    SIRT6 activator 2

    		Sirtuin Metabolic Disease
    SIRT6 activator 2 (compound 31) is a sirtuin 6 activator with anti-lipid accumulation properties. SIRT6 activator 2 significantly downregulates LXR, SREBP-1c, and their target genes associated with lipogenesis, and can be used for research related to lipid metabolism-related diseases .
    SIRT6 activator 2

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