891002-11-2
891002-11-2
Chemical Structure
SIRT6-IN-2
- CAS No.: 891002-11-2
- Formula:C19H14N2O6
- Molecular Weight:366.32
IUPAC Name: 5-(4-(furan-2-carboxamido)benzamido)-2-hydroxybenzoic acid
InChIKey: WCJCTRHTVZUWSD-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(NC(C2=CC=CO2)=O)C=C1)NC3=CC(C(O)=O)=C(O)C=C3
Biological Activity: SIRT6-IN-2 (Compound 5) is a selective and competitive SIRT6 inhibitor (IC50: 34 μM). SIRT6-IN-2 increases acetylation of H3K9 and increases glucose uptake in cultured cells. SIRT6-IN-2 also reduces T cell proliferation. SIRT6-IN-2 has immunosuppressive and chemosensitizing effects[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SIRT6-IN-2 | 99.92% | SIRT6-IN-2 (Compound 5) is a selective and competitive SIRT6 inhibitor (IC50: 34 μM). SIRT6-IN-2 increases acetylation of H3K9 and increases glucose uptake in cultured cells. SIRT6-IN-2 also reduces T cell proliferation. SIRT6-IN-2 has immunosuppressive and chemosensitizing effects. | ||||||||||||||||||||
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SIRT6-IN-2 (Standard) | ≥98% | SIRT6-IN-2 (Standard) is the analytical standard of SIRT6-IN-2 (HY-103721). This product is intended for research and analytical applications. SIRT6-IN-2 (Compound 5) is a selective and competitive SIRT6 inhibitor (IC50: 34 μM). SIRT6-IN-2 increases acetylation of H3K9 and increases glucose uptake in cultured cells. SIRT6-IN-2 also reduces T cell proliferation. SIRT6-IN-2 has immunosuppressive and chemosensitizing effects. | ||||||||||||||||||||
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