1214468-35-5
1214468-35-5
Chemical Structure
SIRT2/6-IN-1
- CAS No.: 1214468-35-5
- Formula:C19H14N4O5S
- Molecular Weight:410.40
IUPAC Name: 2,4-dioxo-N-(4-(pyridin-3-yloxy)phenyl)-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
InChIKey: CNILPKOOBRBNEQ-UHFFFAOYSA-N
SMILES: O=S(C1=CC2=C(C=C1)NC(NC2=O)=O)(NC3=CC=C(C=C3)OC4=CC=CN=C4)=O
Biological Activity: SIRT2/6-IN-1 (Compound 5) is a SIRT6/SIRT2 inhibitor, with IC50s of 106 μM and 114 μM. SIRT2/6-IN-1 increases H3K9 acetylation, increases glucose uptake and reduces TNF-α secretion in cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SIRT2/6-IN-1 | 99.79% | SIRT2/6-IN-1 (Compound 5) is a SIRT6/SIRT2 inhibitor, with IC50s of 106 μM and 114 μM. SIRT2/6-IN-1 increases H3K9 acetylation, increases glucose uptake and reduces TNF-α secretion in cells. | ||||||||||||||||||||
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