1 Result for "

SL 052

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SL 052" in MCE Product Catalog:

Cat. No.: HY-19873
CAS No.: 925438-34-2
Target:  

Photosensitizer

Research Areas:  

Cancer

SL-052 is a hypocrellin-based photosensitizer that has recently shown promising results in clinical and preclinical testing for cancer photodynamic therapy (PDT). SL-052 is encapsulated in biodegradable polylactic-co-glycolic acid (PLGA) polymer nanoparticles optimized using single emulsion solvent evaporation technology. The SL-052-PLGA nanoparticles were more effective in PDT treatment of subcutaneous SCCVII squamous cell carcinoma compared to polyvinylpyrrolidone (PVP)-based and standard liposomal SL-052 formulations. A longer time interval between drug injection and tumor illumination can improve tumor cure rates, and SL-052-PLGA nanoparticles showed the best therapeutic effect among all SL-052 formulations.
loading...
    loading...