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SOX9

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Apoptosis (2) DNA/RNA Synthesis (1) MMP (1) Ser/Thr Protease (1) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cardiovascular Disease (1) Inflammation/Immunology (1) Neurological Disease (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

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Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-19820A

NSC45586 sodium 1 Publications Verification	Akt Ser/Thr Protease Apoptosis MMP	Cardiovascular Disease Neurological Disease Inflammation/Immunology
NSC45586 sodium is an inhibitor of PHLPP. NSC45586 sodium targets the PP2C phosphatase domains of PHLPP1 and PHLPP2, blocks the phosphatase activity of PHLPP, increases the expression level of FOXO1 in the nucleus, and reduces the protein expression of PHLPP1. NSC45586 sodium activates the AKT survival signaling pathway, enhances IGF-1-induced AKT activation, and inhibits the phosphorylation of AKT/ERK under basal conditions. NSC45586 sodium reduces staurosporine-induced neuronal death, preserves notochord cell morphology and KRT19 expression, inhibits cell apoptosis (apoptosis), improves the viability and proliferation of nucleus pulposus cells, upregulates the expression of *ACAN/SOX9*, and downregulates the expression of MMP13. NSC45586 sodium binds tightly to bovine serum albumin (bovine serum albumin), and exerts a more significant effect on nucleus pulposus in male individuals. NSC45586 sodium can be used in studies related to global cerebral ischemia and intervertebral disc degeneration .

HY-N12540

Monogalactosyldiacylglycerol MGDG	DNA/RNA Synthesis Apoptosis	Others
Monogalactosyldiacylglycerol (MGDG) is a galactolipid with anti-inflammatory and anticancer activities, which is found in photosynthetic organisms. Monogalactosyldiacylglycerol is a potent DNA polymerase inhibitor with pro-apoptotic activity. Monogalactosyldiacylglycerol inhibits the synthesis of LPS (HY-D1056)-induced inflammation-related proteins (Ex-FABP, Avidin, Serum Amyloid A). Monogalactosyldiacylglycerol exerts an anti-proliferative effect on chicken articular chondrocytes . Monogalactosyldiacylglycerol can be used in research related to osteoarthritis, cancer and inflammatory diseases .

HY-RS23830

Sox9 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sox9 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sox9 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sox9 Rat Pre-designed siRNA Set A Sox9 Rat Pre-designed siRNA Set A

HY-RS13599

SOX9 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SOX9 Human Pre-designed siRNA Set A contains three designed siRNAs for SOX9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SOX9 Human Pre-designed siRNA Set A SOX9 Human Pre-designed siRNA Set A

HY-RS17376

Sox9 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sox9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sox9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sox9 Mouse Pre-designed siRNA Set A Sox9 Mouse Pre-designed siRNA Set A

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N12540

Monogalactosyldiacylglycerol MGDG	Structural Classification other families Oplismenus burmannii Plants Lipid Source Classification	DNA/RNA Synthesis Apoptosis
Monogalactosyldiacylglycerol (MGDG) is a galactolipid with anti-inflammatory and anticancer activities, which is found in photosynthetic organisms. Monogalactosyldiacylglycerol is a potent DNA polymerase inhibitor with pro-apoptotic activity. Monogalactosyldiacylglycerol inhibits the synthesis of LPS (HY-D1056)-induced inflammation-related proteins (Ex-FABP, Avidin, Serum Amyloid A). Monogalactosyldiacylglycerol exerts an anti-proliferative effect on chicken articular chondrocytes . Monogalactosyldiacylglycerol can be used in research related to osteoarthritis, cancer and inflammatory diseases .

Host:	Mouse (2) Rabbit (3)
Reactivity:	Human (5) Rat (2) Mouse (3)
Application:	IHC-P (3) ICC/IF (4) mIHC (1) IF-Tissue (1) IP (1) IHC-F (1) WB (5) FC (1) ELISA (3)
Isotype:	IgG (3) IgG1 (2)
Conjugation:	Non-conjugated (5)
Clonality:	Monoclonal (3) Monoclonal Antibody (1) Recombinant (1)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86675

	SOX9 Antibody (YA6367) CMD 1; CMD1; CMPD 1; CMPD1; SOX 9; SOX9; SOX9_HUMAN; SRA 1; SRA1 antibody SRY(sex determining region Y) box 9(campomelic dysplasia autosomal; SRY(sex determining region Y) box 9; SRY(sex determining region Y)-box 9; SRY(sex-determining region Y)-box 9 protein; Transcription factor SOX 9; Transcription factor SOX-9; transcription factor SOX9; campomelic dysplasia autosomal sex reversal.	WB, IHC-P, IF-Tissue, IHC-F	Human, Mouse, Rat
	SOX9 Antibody (YA6367) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SOX9.

HY-P80335

	SOX9 Antibody (YA065) 2 Publications Verification	WB, IHC-P, ICC/IF, IP, FC, mIHC	Human, Mouse
	SOX9 Antibody (YA065) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SOX9.

HY-P86577

	SOX9 Antibody (YA6269)	WB, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat
	SOX9 Antibody (YA6269) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SOX9.

HY-P84349

	SOX9 Antibody (YA4046) CMD1; SRA1; CMPD1	WB, ICC/IF, ELISA	Human
	SOX9 Antibody (YA4046) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SOX9.

HY-P84349A

	SOX9 Antibody (YA4046)(PBS only) CMD1; SRA1; CMPD1	WB, ICC/IF, ELISA	Human
	SOX9 Antibody (YA4046) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SOX9.

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Sox9 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Sox9 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sox9 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

SOX9 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SOX9 Human Pre-designed siRNA Set A contains three designed siRNAs for SOX9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sox9 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Sox9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sox9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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