1 Result for "

SRI31255

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SRI31255" in MCE Product Catalog:

Cat. No.: HY-75368
CAS No.: 905580-86-1
Target:  

LRRK2

Domaines de recherche:  

Neurological Disease

SRI-31255 is an orally active LRRK2 inhibitor with IC50 values of 520 and 427 nM for human wild-type (WT) and mutant G2019S, respectively. SRI-31255 exerts neuroprotective effects by binding to the ATP-binding pocket of LRRK2, inhibiting kinase activity. SRI-31255 can be used as a lead compound for the development of LRRK2-targeted drugs for the treatment of Parkinson's disease .
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