SRI-31255
Based on 1 Customer Validation
SRI-31255 is an orally active LRRK2 inhibitor with IC50 values of 520 and 427 nM for human wild-type (WT) and mutant G2019S, respectively. SRI-31255 exerts neuroprotective effects by binding to the ATP-binding pocket of LRRK2, inhibiting kinase activity. SRI-31255 can be used as a lead compound for the development of LRRK2-targeted drugs for the treatment of Parkinson's disease.
For research use only. We do not sell to patients.
- Purity: 99.88%
- CAS No.: 905580-86-1
- Formula: C15H14N4
- Molecular Weight:250.30
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 905580-86-1
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Appearance Solid
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Molecular Weight 250.30
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Formula C15H14N4
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Color White to light yellow
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SMILES
C1(N[C@@H](CC2)C3=C2C=CC=C3)=C4C(NC=C4)=NC=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)