3 Results for "

SYN1436

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "SYN1436" in MCE Product Catalog:

Cat. No.: HY-P11882
CAS No.: 947545-69-9
Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

SYN1436 is a selective human neonatal Fc receptor (hFcRn) antagonist with an IC50 of 2.4 nM. SYN1436 binds to hFcRn and inhibits hFcRn-hIgG interaction. SYN1436 can be used for the research of autoimmune diseases .
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Cat. No.: HY-P11786
CAS No.: 1020264-43-0
Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

SYN1327 is a potent monomeric cyclic competitive antagonistic peptide targeting the neonatal Fc receptor (FcRn), with a Kd of 31 nM for human FcRn at pH 6 and a Kd of 170 nM at pH 7.4. SYN1327 competitively binds to the IgG-binding site of FcRn and inhibits the binding of human IgG to FcRn. SYN1327 acts as the monomeric precursor of the dimeric peptide SYN1436 (HY-P11882). SYN1327 can be used in studies related to IgG-mediated autoimmune diseases .
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Cat. No.: HY-P11786A
Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

SYN1327 acetate is a potent monomeric cyclic competitive antagonistic peptide targeting the neonatal Fc receptor (FcRn), with a Kd of 31 nM for human FcRn at pH 6 and a Kd of 170 nM at pH 7.4. SYN1327 acetate competitively binds to the IgG-binding site of FcRn and inhibits the binding of human IgG to FcRn. SYN1327 acetate acts as the monomeric precursor of the dimeric peptide SYN1436 (HY-P11882). SYN1327 acetate can be used in studies related to IgG-mediated autoimmune diseases .
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