1020264-43-0
Chemical Structure
SYN1327
- CAS No.: 1020264-43-0
- Formula:C72H101N19O16S2
- Molecular Weight:1552.82
InChIKey: OOEOTYYQESNHNZ-ZTYWXYLJSA-N
SMILES: O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](C(C)(SSC[C@@H](C(N)=O)NC2=O)C)C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](CC3=CNC=N3)C(N[C@@H](CC4=CC=CC=C4)C(NCC(N(C)CC(N(C)[C@@H](CC(C)C)C(N[C@@H](CC5=CC=C(C=C5)O)C(N6[C@H]2CCC6)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C
Biological Activity: SYN1327 is a monomeric peptide that selectively inhibits the hIgG-hFcRn interaction. SYN1327 binds to soluble human FcRn (shFcRn) with Kd values of 31 nM and 170 nM at pH 6 and 7.4, respectively[1].
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SYN1327 | SYN1327 is a monomeric peptide that selectively inhibits the hIgG-hFcRn interaction. SYN1327 binds to soluble human FcRn (shFcRn) with Kd values of 31 nM and 170 nM at pH 6 and 7.4, respectively. | |||||||||||||||||||||
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Keywords
