5 Results for "

Seneciphylline

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Seneciphylline" in MCE Product Catalog:

Cat. No.: HY-N1282
CAS No.: 480-81-9
Seneciphylline is an orally effective hepatotoxic inducer. Seneciphylline is metabolized by CYP450 enzymes into active intermediates, which covalently bind to intracellular biomacromolecules such as proteins and DNA to form adducts, which in turn trigger a series of toxic reactions, such as inducing cell apoptosis and damaging mitochondrial function. Seneciphylline can be used in hepatotoxicity research[1][2].
loading...
    loading...
Cat. No.: HY-N1282R
CAS No.: 480-81-9
Seneciphylline (Standard) is the analytical standard of Seneciphylline. This product is intended for research and analytical applications. Seneciphylline is a toxic pyrrolizidine alkaloid in Gynura japonica . Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities .
loading...
    loading...
Cat. No.: HY-N2561
CAS No.: 38710-26-8
Seneciphylline N-Oxide is a dehydrogenation product of Senecionine N-oxide. Seneciphylline N-Oxide is a natural compound isolated from root cultures of Senecio erucifolius (Asteraceae) .
loading...
    loading...
Cat. No.: HY-N6848
CAS No.: 123844-00-8
Target:  

Drug Derivative

Research Areas:  

Infection

Acetylseneciphylline N-oxide is a pyrrolizine alkaloid that is seneciphylline in which the hydroxy hydrogen is replaced by an acetyl group and the tertiary amino function is oxidised to the corresponding N-oxide .
loading...
    loading...
Cat. No.: HY-N19746
CAS No.: 80151-77-5
Tussilagine is a non-toxic pyrrolizidine alkaloid present in the inflorescences of Arnica montana, A. chamissonis ssp. foliosa, A. amplexicaulis, A. sachalinensis, and Tussilago farfara L.. Tussilagine exhibits chromosome damaging activity .
loading...
    loading...