1. Metabolic Enzyme/Protease
  2. Gutathione S-transferase
    Cytochrome P450
  3. Seneciphylline

Seneciphylline 

Cat. No.: HY-N1282
Handling Instructions

Seneciphylline is a toxic pyrrolizidine alkaloid in Senecio plants. Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities.

For research use only. We do not sell to patients.

Seneciphylline Chemical Structure

Seneciphylline Chemical Structure

CAS No. : 480-81-9

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Description

Seneciphylline is a toxic pyrrolizidine alkaloid in Senecio plants[1]. Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities[2].

Molecular Weight

333.38

Formula

C₁₈H₂₃NO₅

CAS No.

480-81-9

SMILES

O=C(O[[email protected]]1([H])CCN2[[email protected]]1([H])C(COC([[email protected]](C)(O)C(C/3)=C)=O)=CC2)C3=C/C

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

SeneciphyllineGutathione S-transferaseCytochrome P450Glutathione transferasesGSTsCYPsToxicpyrrolizidinealkaloidepoxidehydraseglutathione-S-transferasecytochromeP-450Inhibitorinhibitorinhibit

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