80151-77-5
80151-77-5
Chemical Structure
Tussilagine
- CAS No.: 80151-77-5
- Formula:C10H17NO3
- Molecular Weight:199.25
InChIKey: LADVYSUMGRTFSZ-QXFUBDJGSA-N
SMILES: COC([C@H]1[C@@]2([H])N(CCC2)C[C@]1(O)C)=O
Biological Activity: Tussilagine is a non-toxic pyrrolizidine alkaloid present in the inflorescences of Arnica montana, A. chamissonis ssp. foliosa, A. amplexicaulis, A. sachalinensis, and Tussilago farfara L.. Tussilagine exhibits chromosome damaging activity[1][2][3][4].
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Tussilagine | Tussilagine is a non-toxic pyrrolizidine alkaloid present in the inflorescences of Arnica montana, A. chamissonis ssp. foliosa, A. amplexicaulis, A. sachalinensis, and Tussilago farfara L.. Tussilagine exhibits chromosome damaging activity. | |||||||||||||||||||||
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References
- [1]. Paßreiter CM, et al. Tussilagine and isotussilagine: two pyrrolizidine alkaloids in the genus Arnica. Presented at: 39th Annual Congress on Medicinal Plant Research; 1991 Sep 3-7; Saarbrücken, Germany. Planta Med. 1991;57:A106.
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[2]. Nedelcheva A, et al. Pyrrolizidine alkaloids in Tussilago farfara from Bulgaria. Biotechnol Biotechnol Equip. 2015;29(Suppl 1):S1-S7.
- [3]. Dreger M, et al. Pyrrolizidine alkaloids - chemistry, biosynthesis, pathway, toxicity, safety and perspectives of medicinal usage. Herba Pol. 2009;55(4):127-147.
- [4]. Behninger C, et al. Wirkung eines Alkaloidextraktes von Symphytum officinale auf menschliche Lymphocytenkulturen [Studies on the effect of an alkaloid extract of Symphytum officinale on human lymphocyte cultures]. Planta Med. 1989 Dec;55(6):518-22. German. [Content Brief]
Keywords
