1 Result for "

Solimastat

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Solimastat" in MCE Product Catalog:

Cat. No.: HY-180412
CAS No.: 226072-63-5
Synonyms: BB-3644
Target:  

MMP

Research Areas:  

Cancer

Solimastat (BB-3644) is a potent metalloproteinase (MMP) inhibitor that blocks constitutive and antibody-stimulated CD30 shedding from cell surfaces with an IC50 of 180 nM. Solimastat enhances persistence of anti-CD30 antibody Ki-3 on cells and favors its internalization. Solimastat enhances cytotoxic activity of Ki-3.dgA towards CD30 + L540 cells. Solimastat can be used for the research of CD30 + malignancies .
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