1 Result for "

Syn516

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Syn516" in MCE Product Catalog:

Cat. No.: HY-125984
CAS No.: 695209-67-7
Target:  

α-synuclein

Research Areas:  

Neurological Disease

Syn-516 is an inhibitor of α-synuclein (α-Syn). Syn-516 targets the 5' untranslated region (5'UTR) of α-Syn mRNA, with an IC50 value of 1.8 μM, thereby inhibiting the translation process of α-Syn. Syn-516 improves motor dysfunction and colonic motility abnormalities associated with α-Syn overexpression in mouse models. α-Syn can be used to study diseases such as Parkinson's disease and Lewy body dementia .
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