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Syn-516

Syn-516 is an inhibitor of α-synuclein (α-Syn). Syn-516 targets the 5' untranslated region (5'UTR) of α-Syn mRNA, with an IC50 value of 1.8 μM, thereby inhibiting the translation process of α-Syn. Syn-516 improves motor dysfunction and colonic motility abnormalities associated with α-Syn overexpression in mouse models. α-Syn can be used to study diseases such as Parkinson's disease and Lewy body dementia.

For research use only. We do not sell to patients.

  • CAS No.: 695209-67-7
  • Formula: C17H17N9S
  • Molecular Weight:379.44
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Syn-516 Chemical Structure
    Syn-516 Chemical Structure
CAS No.: 695209-67-7
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All α-synuclein Isoforms

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    Syn-516 Chemical Structure
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  • Syn-516