1 Result for "

TAT-M2NX

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "TAT-M2NX" in MCE Product Catalog:

TAT-M2NX
TAT-M2NX
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Cat. No.: HY-P5883
CAS No.: 2126166-03-6
Synonyms: TATM2NX
Target:  

TRP Channel

Research Areas:  

Cardiovascular Disease Neurological Disease

TAT-M2NX (tatM2NX) is a selective inhibitor targeting human TRPM2 channels and exerts inhibitory effects on ischemic stroke. TAT-M2NX reduces H2O2-induced calcium influx via TRPM2 channels. After traumatic brain injury in mice, TAT-M2NX preserves hippocampal long-term potentiation, improves memory function, and reduces infarct volume after middle cerebral artery occlusion, but it shows no effect on female mice. TAT-M2NX can be used in studies related to traumatic brain injury and ischemic stroke [2].
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