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Results for "

TCR-IN-1

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

3

Peptides

1

Inhibitory Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P5411
    OVA-T4 Peptide

    SIITFEKL, OVA (257-264) Variant

    		 MHC Others
    OVA-T4 Peptide (SIITFEKL, OVA (257-264) Variant) is a low-affinity variant of OVA (257-264) (SIINFEKL). OVA-T4 Peptide has similar binding to H-2Kb MHC class I molecules as OVA (257-264), but has a much lower affinity for the OT-I TCR25 .
    OVA-T4 Peptide
  • HY-163372
    PROTAC HPK1 Degrader-1

    		PROTACs MAP4K Cancer
    PROTAC HPK1 Degrader-1 (Compound B1) is a potent HPK1 degrader with DC50 value of 1.8 nM. PROTAC HPK1 Degrader-1 inhibits phosphorylation of the SLP76 protein with IC50 value of 496.1 nM. PROTAC HPK1 Degrader-1 is a bona fide HPK1-PROTAC degrader, which provided a potential tool for further HPK1 investigation in TCR signaling .
    PROTAC HPK1 Degrader-1
  • HY-P990303
    Anti-Mouse 2C TCR Antibody (1B2)

    		Nuclear Factor of activated T Cells (NFAT) Others
    Anti-Mouse 2C TCR Antibody (1B2) is a mouse-derived IgG1 type antibody inhibitor, targeting to mouse 2C TCR. Anti-Mouse 2C TCR Antibody (1B2) recognizes determinants on the variable regions of both the α and β subunits of the TCR (T cell receptor) expressed by the mouse cytotoxic T lymphocyte clone 2C. Anti-Mouse 2C TCR Antibody (1B2) can be used for the detections of immunofluorescence and flow cytometry [1].
    Anti-Mouse 2C TCR Antibody (1B2)
  • HY-180608
    TCR-IN-1

    		Interleukin Related IFNAR Inflammation/Immunology
    TCR-IN-1 (Compound A-33) is a TCR inhibitor. TCR-IN-1 blocks cytokine (IL-2, TNFα, IFNγ, IL-17A) release [1].
    TCR-IN-1
  • HY-P5917A
    Vm24-toxin TFA

    Vaejovis mexicanus peptide 24 TFA

    		 Potassium Channel Inflammation/Immunology Cancer
    Vm24-toxin (Vaejovis mexicanus peptide 24) TFA, a 36-residue peptide, is a potent and selective Kv1.3 blocker with a Kd of ~3 pM in lymphocytes. Vm24-toxin TFA shows >1500-fold affinity for Kv1.3 over other assayed potassium channels. Vm24-toxin TFA folds into a distorted cystine-stabilized α/β motif consisting of a single-turn α-helix and a three-stranded antiparallel β-sheet, stabilized by four disulfide bridges. Vm24-toxin TFA attenuates the CD4 + effector memory T cell response to T cell receptor (TCR) stimulation .
    Vm24-toxin TFA
  • HY-P5917
    Vm24-toxin

    Vaejovis mexicanus peptide 24

    		 Potassium Channel Inflammation/Immunology Cancer
    Vm24-toxin (Vaejovis mexicanus peptide 24), a 36-residue peptide, is a potent and selective Kv1.3 blocker with a Kd of ~3 pM in lymphocytes. Vm24-toxin shows >1500-fold affinity for Kv1.3 over other assayed potassium channels. Vm24-toxin folds into a distorted cystine-stabilized α/β motif consisting of a single-turn α-helix and a three-stranded antiparallel β-sheet, stabilized by four disulfide bridges. Vm24-toxin attenuates the CD4 + effector memory T cell response to T cell receptor (TCR) stimulation .
    Vm24-toxin

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