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Referencia número: HY-180608

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TCR-IN-1

TCR-IN-1 (Compound A-33) is a TCR inhibitor. TCR-IN-1 blocks cytokine (IL-2, TNFα, IFNγ, IL-17A) release.

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No. CAS: 2375042-31-0
Fòrmula: C₂₃H₂₄FNO₄
Peso molecular:397.44

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

TCR-IN-1 Chemical Structure

No. CAS: 2375042-31-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Actividad biológica

Descripciòn

TCR-IN-1 (Compound A-33) is a TCR inhibitor. TCR-IN-1 blocks cytokine (IL-2, TNFα, IFNγ, IL-17A) release^[1].

IC₅₀ & Target^[1]

IL-2

IL-17A

Ver todos los productos específicos de isoformas Interleukin Related :

Chemical Information

No. CAS 2375042-31-0
Peso molecular 397.44
Fòrmula C₂₃H₂₄FNO₄
SMILES

FC(C=C1)=CC=C1C2=C(CN3CCCC3)COC4=CC=C(OCCC(O)=O)C=C42
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Christopher Loren Vandeusen, et al. Combination of a chromene derivative tcr inhibitor and a pde4 inhibitor. WO2025255109A1. WIPO (PCT). 2025-06-03.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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TCR-IN-1

Ver todos los productos específicos de isoformas Interleukin Related

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

TCR-IN-1 Related Classifications

HY-180608 Related Classifications