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TMEM175 modulator

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-162666

    Potassium Channel Neurological Disease
    TMEM175 modulator 1 (compound 47) is a TMEM175 modulator.TMEM175 modulator 1 modulates activity of the lysosomal potassium ion channel TMEM175.TMEM175 modulator 1 can be used for the research of parkinson’s disease, dementia, alzheimer’s disease, l-dopa induced dyskinesia .
    TMEM175 modulator 1
  • HY-161949
    AP-6
    1 Publications Verification

    Potassium Channel Neurological Disease
    AP-6 is a selective inhibitor of TMEM175 with activity in modulating lysosomal function. Acute inhibition of TMEM175 by AP-6 increases lysosomal macromolecular catabolism, thereby accelerating macrophage and other digestive processes. AP-6 may be used in Parkinson's disease research .
    AP-6
  • HY-182768

    Potassium Channel Neurological Disease
    TMEM175 modulator 4 (Compound 3) is a TMEM175 modulator. TMEM175 modulator 4 modulates the activity of the lysosomal potassium channel TMEM175. TMEM175 modulator 4 can be used for research related to Parkinson's disease .
    TMEM175 modulator-4
  • HY-181622

    Potassium Channel Neurological Disease
    TMEM175 modulator 3 (Compound 14) is a TMEM175 modulator. TMEM175 modulator 3 can be used in research on neurodegenerative diseases .
    TMEM175 modulator 3
  • HY-181621

    Potassium Channel Neurological Disease
    Tmem175 modulator 2 (example 180) is a TMEM175 modulator.Tmem175 modulator 2 can be used for the research of neurodegenerative disorders .
    Tmem175 modulator 2
  • HY-182464

    Potassium Channel Infection Others
    DABMA is a TMEM175 channel activator with a human EC50 of 17.9 μM. DABMA directly increases TMEM175 channel current via interaction with intracellular, transmembrane, or endosomal lumen-associated domains, and does not alter TMEM175 mRNA or protein levels. DABMA delays endolysosomal substrate degradation, modulates endolysosomal trafficking, increases acidic organelle accumulation, induces cholesterol accumulation and altered late endosome morphology. DABMA can be used for the research of coronavirus disease, Clostridium difficile infection, Pseudomonas aeruginosa infection, rabies, and influenza virus infection .
    DABMA

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