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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
TMEM175 modulator
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "TMEM175 modulator" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-161949
CAS No.: 1369963-51-8
Target:
Domaines de recherche:
AP-6 is a selective inhibitor of TMEM175 with activity in modulating lysosomal function. Acute inhibition of TMEM175 by AP-6 increases lysosomal macromolecular catabolism, thereby accelerating macrophage and other digestive processes. AP-6 may be used in Parkinson's disease research .
Cat. No.: HY-162666
CAS No.: 3038770-25-8
Target:
Domaines de recherche:
TMEM175 modulator 1 (compound 47) is a TMEM175 modulator.TMEM175 modulator 1 modulates activity of the lysosomal potassium ion channel TMEM175.TMEM175 modulator 1 can be used for the research of parkinson’s disease, dementia, alzheimer’s disease, l-dopa induced dyskinesia .
Cat. No.: HY-182768
CAS No.: 3119251-34-9
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Domaines de recherche:
TMEM175 modulator 4 (Compound 3) is a TMEM175 modulator. TMEM175 modulator 4 modulates the activity of the lysosomal potassium channel TMEM175. TMEM175 modulator 4 can be used for research related to Parkinson's disease .
Cat. No.: HY-181622
CAS No.: 3115239-67-0
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Domaines de recherche:
TMEM175 modulator 3 (Compound 14) is a TMEM175 modulator. TMEM175 modulator 3 can be used in research on neurodegenerative diseases .
Cat. No.: HY-181621
Target:
Domaines de recherche:
Tmem175 modulator 2 (example 180) is a TMEM175 modulator.Tmem175 modulator 2 can be used for the research of neurodegenerative disorders .
Cat. No.: HY-182464
CAS No.: 893603-33-3
Target:
DABMA is a TMEM175 channel activator with a human EC50 of 17.9 μM. DABMA directly increases TMEM175 channel current via interaction with intracellular, transmembrane, or endosomal lumen-associated domains, and does not alter TMEM175 mRNA or protein levels. DABMA delays endolysosomal substrate degradation, modulates endolysosomal trafficking, increases acidic organelle accumulation, induces cholesterol accumulation and altered late endosome morphology. DABMA can be used for the research of coronavirus disease, Clostridium difficile infection, Pseudomonas aeruginosa infection, rabies, and influenza virus infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
