2 Results for "

TPP23411

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "TPP23411" in MCE Product Catalog:

Cat. No.: HY-P991942
Synonyms: BAY3375968; TPP-23411

Target:  

CCR

Research Areas:  

Inflammation/Immunology Cancer

Lanerkitug (BAY3375968) is a fully human monoclonal IgG1 anti-human CCR8 antibody. Lanerkitug selectively depletes human CCR8 + Tregs via antibody dependent cellular cytotoxicity (ADCC) and antibody dependent cellular phagocytosis (ADCP). Lanerkitug can be used in the research of solid tumors .
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Cat. No.: HY-P991942A
Synonyms: BAY3375968 (FUT8-KO); TPP-23411 (FUT8-KO)

Target:  

CCR

Research Areas:  

Cancer

Lanerkitug (FUT8-KO) (BAY3375968 (FUT8-KO)) is an anti-CCR8 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the ADCC effect of the antibody. Lanerkitug (HY-P991942) selectively depletes human CCR8+Tregs via antibody dependent cellular cytotoxicity (ADCC) and antibody dependent cellular phagocytosis (ADCP). Lanerkitug can be used in the research of solid tumors .
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