Lanerkitug (FUT8-KO)

(Synonyms: BAY3375968 (FUT8-KO); TPP-23411 (FUT8-KO))

Lanerkitug (FUT8-KO) (BAY3375968 (FUT8-KO)) is an anti-CCR8 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the ADCC effect of the antibody. Lanerkitug (HY-P991942) selectively depletes human CCR8+Tregs via antibody dependent cellular cytotoxicity (ADCC) and antibody dependent cellular phagocytosis (ADCP). Lanerkitug can be used in the research of solid tumors.

For research use only. We do not sell to patients.

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    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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