1 Result for "

TRPC6-PAM-C20

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TRPC6-PAM-C20" in MCE Product Catalog:

Cat. No.: HY-136190
CAS No.: 667427-75-0
Purity:  99.78%
Target:  

TRP Channel

Research Areas:  

Neurological Disease

TRPC6-PAM-C20 is a selective positive allosteric modulator (PAM) of TRPC6 channels. TRPC6-PAM-C20 is a potent enhancer of channel activation, enabling low basal concentrations of DAG to induce activation of the ion channel. TRPC6-PAM-C20 induces increases in intracellular Ca 2+ concentrations ([Ca 2+]i) in TRPC6-expressing HEK293 cells with an EC50 of 2.37 μM. TRPC6-PAM-C20 can be used as a valuable tool to selectively exaggerate TRPC6-dependent signals .
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