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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
Tomatine
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "Tomatine" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-N2166
CAS No.: 17406-45-0
Synonyms: α-Tomatine; Lycopersicin; Tomatin
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Target:
Cat. No.: HY-N2166R
CAS No.: 17406-45-0
Synonyms: α-Tomatine (Standard); Lycopersicin (Standard); Tomatin (Standard)
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Target:
5-Dehydroepisterol is a C28 alkylated sterol based on ergostane, and serves as a major component of the sterol pool in Leishmania parasites. The content of 5-Dehydroepisterol in Leishmania promastigotes can be depleted by 22,26-Azasterol, Amiodarone (HY-14187) and Tomatine (HY-N2166). Among these agents, Amiodarone (HY-14187) inhibits the biosynthetic process of this sterol by disrupting the function of squalene epoxidase. 5-Dehydroepisterol can be used in the research of leishmaniasis and cutaneous leishmaniasis .
Cat. No.: HY-N2166A
CAS No.: 17605-83-3
Synonyms: α-Tomatine hydrochloride; Lycopersicin hydrochloride; Tomatin hydrochloride
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Research Areas:
Tomatine hydrochloride is a glycoalkaloid, found in the tomato plant (Lycopersicon esculentum Mill.). Tomatine hydrochloride elicits neurotoxicity in RIP1 kinase and caspase-independent manner. Tomatine hydrochloride promotes the upregulation of nuclear apoptosis inducing factor (AIF) in neuroblastoma cells. Tomatine hydrochloride also inhibits 20S proteasome activity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
