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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
U 50488
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "U 50488" in MCE Product Catalog:
Cat. No.: HY-130696
CAS No.: 67198-17-8
Synonyms: (+)-Trans-(1R,2R)-U-50488
Target:
Research Areas:
(+)-U-50488 ((+)-Trans-(1R,2R)-U-50488) is a less active κ opioid receptor (KOR) agonist than the enantiomer of (-)-Trans-(1S,2S)-U-50488 (HY-15997) .
Cat. No.: HY-130696A
CAS No.: 67198-13-4
Synonyms: (±)-trans-(1R,2R)-U-50488
Target:
Research Areas:
(±)-U-50488 ((±)-trans-(1R,2R)-U-50488) is a selective kappa opioid receptor agonist. (±)-U-50488 can improve symptoms related to status epilepticus, but has no significant effect on spontaneous seizure episodes. (±)-U-50488 can be used for research of epilepsy .
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1 Cited Publications
Cat. No.: HY-15997
CAS No.: 114528-79-9
Synonyms: (-)-Trans-(1S,2S)-U-50488 hydrochloride
Target:
(-)-U-50488 hydrochloride ((-)-Trans-(1S,2S)-U-50488 hydrochloride) is a selective kappa-opioid receptor (KOR) agonist (Kd=2.2 nM) over μ-opioid receptor (MOR) (Kd=430 nM). (-)-U-50488 hydrochloride is a more active enantiomer than (+) trans-(1R,2R) U-50488 (HY-15997A) or the (±) trans-racemic mixture U-50488 (HY-15997B). (-)-U-50488 hydrochloride has a potent and sustained anti-HIV effect in fected blood monocyte-derived macrophages (MDM) .
Cat. No.: HY-15997B
CAS No.: 67197-96-0
Synonyms: (±)-Trans-(1R,2R)-U-50488 hydrochloride
Target:
Research Areas:
(±)-U-50488 ((±)-Trans-(1R,2R)-U-50488) hydrochloride is a selective κ opioid receptor (KOR) agonist .
Cat. No.: HY-15997C
Synonyms: (±)-Trans-(1R,2R)-U-50488 hydrate hydrochloride
Target:
Research Areas:
(±)-U-50488 ((±)-Trans-(1R,2R)-U-50488) hydrate hydrochloride is a selective κ opioid receptor (KOR) agonist .
Target:
Research Areas:
(1R,2R)-U-50488 hydrochloride is the absolute stereochemistry of (±)-U-50488 hydrochloride. (±)-U-50488 hydrochloride is a selective κ opioid receptor (KOR) agonist .
Cat. No.: HY-139390
CAS No.: 1339332-99-8
Target:
Research Areas:
3,4-Difluoro U-50488 hydrochloride is a utopioid.
Cat. No.: HY-15997A
CAS No.: 114528-81-3
Synonyms: (+)-Trans-(1R,2R)-U-50488 hydrochloride
Target:
Research Areas:
(+)-U-50488 (hydrochloride) (+)-Trans-(1R,2R)-U-50488 hydrochloride) is a less active κ opioid receptor (KOR) agonist than the enantiomer of (-)-Trans-(1S,2S)-U-50488 (HY-15997) .
Cat. No.: HY-P5756
CAS No.: 3032600-19-1
Target:
Research Areas:
Cat. No.: HY-119733
CAS No.: 1541206-05-6
Target:
Research Areas:
BU09059 is a potent and selective Kappa-opioid receptor antagonist with a pA2 of 8.62. BU09059 has nanomolar affinity for the κ-receptor, with 15-fold and 616-fold selectivity over μ- and δ-receptors, respectively. BU09059 significantly blocks U50488 (HY-15997B)-induced antinociception .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
