1 Result for "

UCCF029

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "UCCF029" in MCE Product Catalog:

Cat. No.: HY-128131
CAS No.: 2110-25-0
Target:  

Endogenous Metabolite

Research Areas:  

Others

UCCF-029 Free base is a potent activator of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel. UCCF-029 Free base exhibits enhanced activity through benzannulation of the flavone A-ring at the 7,8-position. UCCF-029 Free base serves as a structural guide for the development of more effective flavonoid analogues. UCCF-029 Free base demonstrates improved potency compared to apigenin in activating wild-type CFTR. UCCF-029 Free base also exhibits potential for activating the mutant CFTR (G551D-CFTR) though not as robustly as apigenin.
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