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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
UD-CG115
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "UD-CG115" in MCE Product Catalog:
3
Target:
Research Areas:
Pimobendan (UD-CG115) is a selective inhibitor of PDE3 with IC50 of 0.32 μM.
Cat. No.: HY-B0204S1
Synonyms: UD-CG115-d3
Cat. No.: HY-B0204A
CAS No.: 77469-98-8
Synonyms: UD-CG115 hydrochloride
Target:
Research Areas:
Pimobendan hydrochloride (UD-CG115 hydrochloride) is a selective inhibitor of PDE3 with IC50 of 0.32 μM.
Cat. No.: HY-B0204R
CAS No.: 74150-27-9
Synonyms: UD-CG115 (Standard)
Research Areas:
Pimobendan (Standard) is the analytical standard of Pimobendan. This product is intended for research and analytical applications. Pimobendan (UD-CG115) is a selective inhibitor of PDE3 with IC50 of 0.32 μM.
Cat. No.: HY-B0204S2
Synonyms: UD-CG115-d4
Cat. No.: HY-B0204B
CAS No.: 118428-37-8
Synonyms: (-)-UD-CG115
Target:
Research Areas:
(-)-Pimobedan is an isomer of pimobedan. It has the property of stereoselective partitioning or distribution into erythrocytes. The clearance of (-)-pimobedan from erythrocytes is significantly lower than that of (+)-pimobedan, which is entirely due to its stereoselective distribution into erythrocytes. This stereoselective property of (-)-pimobedan may explain the phenomenon previously reported that it produces a 1.5-fold greater contractile force than the (+)-isomer in detergent-treated myocardial specimens of guinea pigs and dogs. These properties suggest that (-)-pimobedan may have unique advantages in terms of in vivo distribution and pharmacological action, which may have important implications for its clinical use.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
