1 Result for "

UNC3474

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "UNC3474" in MCE Product Catalog:

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Cat. No.: HY-156906
CAS No.: 1648707-79-2
Purity:  98.15%
Target:  

MDM-2/p53

Research Areas:  

Cancer

UNC3474 is a small molecule ligand, binding with 53BP1. UNC3474 binds the aromatic methyl-lysine binding cage of 53BP1 TT, with a dissociation constant (Kd) of 1.0 ± 0.3 μM. UNC3474 inhibits the recruitment of 53BP1 to DSBs by stabilizing a pre-existing autoinhibited state of 53BP1 in cells .
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