Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
VKORC1
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "VKORC1" in MCE Product Catalog:
Cat. No.: HY-RS15659
Target:
Research Areas:
VKORC1 Human Pre-designed siRNA Set A contains three designed siRNAs for VKORC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-14854A
CAS No.: 1004551-83-0
Synonyms: ATI-5923 sodium
Target:
Research Areas:
Tecarfarin (ATI-5923) sodium is an orally active VKOR inhibitor with an IC50 of 0.67 μM against VKORC1. Tecarfarin sodium blocks the post-translational modification of vitamin K-dependent coagulation factors II, VII, IX and X, reducing their levels and activities. Tecarfarin sodium prolongs prothrombin time, attenuates venous and arterial thrombosis, increases ear incision bleeding volume, and exerts reversible anticoagulant effects. Tecarfarin sodium is applicable to research related to arterial and venous thrombosis as well as other diseases requiring anticoagulation [1] .
Cat. No.: HY-14854R
CAS No.: 867257-26-9
Synonyms: ATI-5923 (Standard)
Target:
Research Areas:
Tecarfarin (ATI-5923) (Standard) is the analytical standard of Tecarfarin. This product is intended for research and analytical applications. Tecarfarin is an orally active VKOR inhibitor with an IC50 of 0.67 μM against VKORC1. Tecarfarin blocks the post-translational modification of vitamin K-dependent coagulation factors II, VII, IX and X, reducing their levels and activities. Tecarfarin prolongs prothrombin time, attenuates venous and arterial thrombosis, increases ear incision bleeding volume, and exerts reversible anticoagulant effects. Tecarfarin is applicable to research related to arterial and venous thrombosis as well as other diseases requiring anticoagulation [1] .
Cat. No.: HY-14854S
Synonyms: ATI-5923-13C,d3
Cat. No.: HY-RS15660
Target:
Research Areas:
VKORC1L1 Human Pre-designed siRNA Set A contains three designed siRNAs for VKORC1L1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P701835
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: VKORC1; Vitamin K Epoxide Reductase Complex Subunit 1; VKCFD2; Vitamin K Dependent Clotting Factors Deficiency 2; Vitamin K1 2,3‑Epoxide Reductase Subunit 1; Vitamin K Oxidoreductase; VKOR; Vitamin K1 Epoxide Reductase (Warfarin‑Sensitive); Vitamin‑K‑Epox
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
