1 Result for "

WPD pocket

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "WPD pocket" in MCE Product Catalog:

Cat. No.: HY-156659
CAS No.: 445406-82-6
Target:  

Phosphatase ERK

Research Areas:  

Inflammation/Immunology

NC1 is a selective non-competitive and allosteric lymphoid-specific tyrosine phosphatase (LYP) inhibitor, with a Ki value 4.3 μM. NC1 allosterically regulates LYP/PTPN22 activity by restricting WPD loop movement. NC1 inhibits LYP activity in lymphoid T cells and enhances T-cell receptor signaling. NC1 can be used for the research of autoimmune diseases .
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