445406-82-6
445406-82-6
Chemical Structure
NC1
- CAS No.: 445406-82-6
- Formula:C29H26N2O7S
- Molecular Weight:546.59
InChIKey: MEYCXOYFLJPZOT-VGXLKVBOSA-N
SMILES: O=C(C1=CC=C(COC2=CC=C(/C=C3S/C(N(C)C/3=O)=N/C4=CC=C(C(OCC)=O)C=C4)C=C2OC)C=C1)O
Biological Activity: NC1 is a selective non-competitive and allosteric lymphoid-specific tyrosine phosphatase (LYP) inhibitor, with a Ki value 4.3 μM. NC1 allosterically regulates LYP/PTPN22 activity by restricting WPD loop movement. NC1 inhibits LYP activity in lymphoid T cells and enhances T-cell receptor signaling. NC1 can be used for the research of autoimmune diseases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NC1 | 98.73% | NC1 is a selective non-competitive and allosteric lymphoid-specific tyrosine phosphatase (LYP) inhibitor, with a Ki value 4.3 μM. NC1 allosterically regulates LYP/PTPN22 activity by restricting WPD loop movement. NC1 inhibits LYP activity in lymphoid T cells and enhances T-cell receptor signaling. NC1 can be used for the research of autoimmune diseases. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.58
HY-18666D77 -
Similarity Score 0.54
HY-124366Slingshot inhibitor D3 -
Similarity Score 0.54
HY-147902VEGFR-2-IN-24 -
Similarity Score 0.51
HY-160296AN-988 -
Similarity Score 0.50
HY-116100(E/Z)-HA155 -
Similarity Score 0.50
HY-19329HA130 -
Similarity Score 0.49
HY-181442CK2-TN03 -
Similarity Score 0.48
HY-157461Glycation-IN-1 -
Similarity Score 0.47
![4,4′-{[1,4-phenylenebis(methylene)]bis(oxy)}dibenzoic acid Chemical Structure](//file.medchemexpress.com/product_pic/hy-w112383.gif)
HY-W1123834,4′-{[1,4-phenylenebis(methylene)]bis(oxy)}dibenzoic acid -
Explore the MedChemAI to find more analogs
![4,4′-{[1,4-phenylenebis(methylene)]bis(oxy)}dibenzoic acid Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w112383.gif)
