1 Result for "

WS-691

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "WS-691" in MCE Product Catalog:

Cat. No.: HY-182253
CAS No.: 2035417-32-2
Target:  

P-glycoprotein

Research Areas:  

Cancer

WS-691 is an orally active, selective ABCB1 modulator. WS-691 selectively stabilizes ABCB1 via direct binding to ABCB1. WS-691 inhibits the efflux function of ABCB1 and activates ABCB1 ATPase activity. WS-691 elevates intracellular Paclitaxel (HY-B0015) levels and reduces the required dose of Paclitaxel in cancer cells overexpressing ABCB1. WS-691 increases the sensitivity of colon cancer cells to Paclitaxel .
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