3 Results for "

WYRGRLC

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "WYRGRLC" in MCE Product Catalog:

Cat. No.: HY-P10739
CAS No.: 1021155-39-4
Target:  

Exosomes Collagen

Research Areas:  

Inflammation/Immunology

WYRGRL is a selective, high-affinity collagen type II-binding peptide with a IC50 of 140 nM. Collagen type II is the most abundant and specific structural protein in the extracellular matrix of articular cartilage. WYRGRL can precisely target small-molecule compounds such as Dexamethasone (HY-14648) and nanocarrier-engineered exosomes to cartilage, significantly enhancing their therapeutic effects on osteoarthritis .
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Cat. No.: HY-P10739C
CAS No.: 1027630-05-2
Target:  

Collagen Apoptosis

Research Areas:  

Inflammation/Immunology

WYRGRLC is a type II collagen-targeting peptide. WYRGRLC specifically binds to type II collagen α1 in articular cartilage in a sequence-dependent manner. WYRGRLC inhibits the binding of WYRGRL-displaying phage (C1-3) to articular cartilage in a sequence-specific manner. WYRGRLC can act as a retention enhancer to improve the cartilage-targeting ability of polymeric nanoparticles and liposomal nanoplatforms, facilitating the delivery of Rapamycin (HY-10219) to chondrocytes. WYRGRLC can be used in studies related to osteoarthritis .
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Cat. No.: HY-P10739E
Research Areas:  

Others

YRLGRWC is a scrambled control of WYRGRLC (HY-P10739C), and it is synthesized by conjugating cysteine to the carboxyl (C-terminus) of YRLGRW (HY-P10739D) .
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