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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
XD2-149
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "XD2-149" in MCE Product Catalog:
Cat. No.: HY-159570
CAS No.: 2710221-08-0
Research Areas:
XD2-149 is a ZFP91 PROTAC degrader with DC50 values of 0.08 μM and 0.06 μM, respectively. ZFP91 is a bifunctional nuclear protein with both transcription factor and E3 ubiquitin ligase activities, and is classified as an oncogenic non-canonical NF-κB pathway regulator in tumor and immune regulation. XD2-149 induces proteasome-dependent degradation of the E3 ubiquitin-protein ligase ZFP91. XD2-149 inhibits the STAT3 signaling pathway in pancreatic cancer cells and induces NQO1-dependent cell death independent of ZFP91 degradation. XD2-149 can be used for the research of pancreatic cancer .
Cat. No.: HY-159571
CAS No.: 2710222-09-4
Research Areas:
Thalidomide-NH-C5-azacyclohexane-N-Boc is an E3 Ligase Ligand-Linker Conjugate. Thalidomide-NH-C5-azacyclohexane-N-Boc can be used to synthesize XD2-149 (HY-159570) .
Cat. No.: HY-159572
Target:
Research Areas:
NH2-C5-Azacyclohexane-N-Boc is a PROTAC linker. NH2-C5-Azacyclohexane-N-Boc can be used in synthesis XD2-149 (HY-159570) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
