1 Result for "

XL118

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "XL118" in MCE Product Catalog:

Cat. No.: HY-167848
CAS No.: 153345-74-5
Synonyms: XL-118
Target:  

Others

Research Areas:  

Cardiovascular Disease

DMP-728 free base (XL-118) is a highly potent and selective GPIIb/IIIa antagonist with antiplatelet and antithrombotic activities. DMP-728 free base can inhibit ADP-induced human platelet aggregation in vitro, with an IC50 of 46 nmol/L, and can significantly reduce the interaction between fibrinogen and human platelets or Binding of purified human GPIIb/IIIa receptors. DMP-728 free base exhibits dose-dependent antiplatelet effects in anesthetized mongrel dogs, effectively inhibiting ADP-induced platelet aggregation and prolonging template bleeding time .
loading...
    loading...