2. Search Result
Search Result
Results for "

XRCC5

" in MedChemExpress (MCE) Product Catalog:

1

Inhibitors & Agonists

1

Recombinant Proteins

1

Antibodies

Cat. No. Compare Product Name Species Source
  • HY-P73846
    Ku70-Ku80 Heterodimer Protein, Human (sf9, His)

    XRCC5-XRCC6 Heterodimer Protein; X-ray repair cross-complementing protein

    		 Human Sf9 insect cells
    The Ku70, a single-stranded DNA-dependent ATP-dependent helicase, is pivotal in DNA non-homologous end joining (NHEJ), central to double-strand break repair and V(D)J recombination. Operating as a DNA helicase II complex with a cell cycle-dependent preference for double-stranded DNA fork-like ends in the 3'-5' direction, it recognizes and binds to broken DNA ends during NHEJ, protecting them from resection. As a DNA-PK regulatory subunit, it enhances PRKDC's affinity to DNA, stabilizes broken DNA ends, and facilitates ligation in NHEJ. The heterodimer may act as a 5'-deoxyribose-5-phosphate lyase (5'-dRP lyase) near double-strand breaks. Beyond DNA repair, it regulates transcription, osteocalcin expression, early ribosome assembly steps, and forms complexes involved in the innate immune response, showcasing its multifaceted cellular functions. Ku70-Ku80 Heterodimer Protein, Human (sf9, His) is a recombinant protein dimer complex containing human-derived Ku70-Ku80 Heterodimer protein, expressed by Sf9 insect cells, with N-His labeled tag. Ku70-Ku80 Heterodimer Protein, Human (sf9, His), has molecular weight of ~70 & 85 kDa, respectively.

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: