1 Result for "

YM928

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "YM928" in MCE Product Catalog:

Cat. No.: HY-118814
CAS No.: 190842-36-5
Target:  

iGluR

Research Areas:  

Neurological Disease

YM928 is an orally active and noncompetitive α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist. YM928 inhibits AMPA receptor-mediated toxicity in primary rat hippocampal cultures with an IC50 value of 2 μM. YM928 blocks AMPA-induced intracellular calcium influx with an IC50 value of 3 μM and antagonizes AMPA-induced inward currents with an IC50 value of 1 μM. YM928 is promising for research of neurological disorders .
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