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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
ZSH-2117
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "ZSH-2117" in MCE Product Catalog:
Cat. No.: HY-174415
ZSH-2117 is an NEDD4-recruiting EGFR PROTAC degrader. ZSH-2117 shows an IC50 of 13 nM against EGFR L858R/T790M/C797S, induces EGFR proteasome-dependent degradation, inhibits the downstream signaling pathways of EGFR, including the phosphorylation of AKT and ERK, suppresses cancer cell proliferation, and exhibits in vivo anti-tumor activity. ZSH-2117 can be used in research related to non-small cell lung cancer .
Cat. No.: HY-175162
Research Areas:
EGFR ligand-20 is a EGFR-binding ligand that serves as a target protein ligand for ZSH-2117 (HY-174415) and is used in studies related to PROTAC synthesis .
Cat. No.: HY-175159
CAS No.: 2223101-36-6
Target:
Research Areas:
3-Phenyl-2H-azirine-2-carboxylic acid is an E3 ubiquitin ligase ligand that can be used in studies related to PROTAC synthesis, such as ZSH-2117 (HY-174415) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
